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Procedure Quick Cards

Bedside procedure references for central line, lumbar puncture, thoracentesis, paracentesis, and arterial line.

Quick-reference cards for common bedside procedures. See Resources by Technique for NEJM Videos and other multimedia guides.

Central Line (CVC)

Site Selection

SiteDepthKey AdvantagesKey Risks
Right IJ~13 cm (or height / 10)Best for ultrasound, compressible, lowest pneumothoraxHigher infection than subclavian per 3SITES
Left IJ~15 cmSame advantages as right IJPleural dome higher on left
Subclavian~15 cm right, ~17 cm leftLowest infection rate (3SITES trial)Highest pneumothorax risk; contraindicated with ipsilateral clavicle fracture
Femoral~20-24 cmCompressible, preferred in coagulopathyHigher infection historically (3SITES showed similar to IJ); avoid if groin infection

Catheter Sizes

CatheterFrench SizeLumensTypical FlowNotes
Triple-lumen7 Fr3 (16 ga, 18 ga, 18 ga)StandardMost common CVC
Sheath introducer (Cordis)8.5 Fr1 (plus sideport)~7.6 L/hr (20 L/hr with pressure bag)Fastest non-HD option; for rapid transfusion or PA catheter
Dialysis catheter11.5-12 Fr2High-flowFor CRRT or HD

Sterile Bundle Checklist

  • Cap, mask, sterile gown, sterile gloves
  • Chlorhexidine skin prep (allow to dry fully)
  • Full-body sterile drape
  • Ultrasound probe cover (sterile)
  • 1% lidocaine for local anesthesia
  • Guidewire, dilator, catheter, suture
  • Saline-flush all ports
  • Verify guidewire exits distal port before dilating
  • Confirm venous placement (manometry, waveform, or blood gas) before dilating

Contraindications

  • Absolute: Infection over site, anatomic obstruction (thrombosis)
  • Relative: Coagulopathy — use compressible site (femoral greater than IJ greater than subclavian). No evidence for prophylactic FFP unless hemophilia or frank arterial puncture

Complications

ComplicationHighest Risk SiteMitigation
PneumothoraxSubclavianUltrasound guidance; use IJ in ventilated patients
Arterial punctureFemoralUltrasound guidance; confirm with manometry
Catheter-related bloodstream infectionFemoral (historical)Maximal sterile barrier; remove when no longer needed
Air embolismAnyTrendelenburg position during insertion; occlude catheter hub
ArrhythmiaAny (guidewire)Advance wire no more than needed; monitor ECG
DVTFemoralMinimize dwell time

WikEM CVC | Merck Manual

Lumbar Puncture

Opening Pressure

  • Normal: 10-20 cm H2O
  • Measure with: Patient in lateral decubitus, legs extended
  • Bacterial meningitis: Often greater than 25 cm H2O

CT Before LP Criteria

Safe to proceed without CT if all of the following are met (NEJM 2001 criteria):

  • Age below 60
  • Not immunocompromised
  • No known CNS disease
  • No seizure within 1 week
  • Alert and following commands
  • Normal neurologic exam

CT findings that prohibit LP: Midline shift, obstructive hydrocephalus, compressed basilar cisterns, posterior fossa mass

Platelet and INR Thresholds

ParameterThresholdAction
Plateletsbelow 25,000Transfuse before LP
INRgreater than 1.5Correct before LP
HemophiliaAnyReplace factor pre-procedure

Tube Order

TubeStudyNotes
Tube 1Cell count and differentialMost likely to have traumatic blood
Tube 2Gram stain, culture (bacterial + viral)Sterile tube for microbiology
Tube 3Glucose, proteinLeast affected by traumatic tap
Tube 4Second cell count or holdFor special tests: crypto Ag, AFB, VDRL, PCR

Bloody tap correction: Subtract 1 WBC per 750 RBC; subtract 1 mg/dL protein per 1000 RBC

CSF Interpretation

PatternWBCDifferentialGlucoseProtein
Bacterialgreater than 100PMN 80-90%Low (below 40)High (greater than 100)
Viral5-500LymphocytesNormalNormal to mildly elevated
Fungal / TB10-500LymphocytesLowHigh
Subarachnoid hemorrhageRBCs presentPMN earlyNormalElevated

Pearls

  • Atraumatic 22-ga needle reduces post-LP headache (2018 Lancet meta-analysis). Needle larger than 20 ga doubles headache risk
  • CSF cultures may be negative 2 hr after parenteral antibiotics (meningococcal) or 6 hr (pneumococcal)
  • Needle gauge: use 22 ga atraumatic when available; reserve 20 ga for obese patients or when opening pressure is critical

WikEM LP | Merck Manual

Thoracentesis

Pre-Procedure Labs

ParameterThresholdNotes
Plateletsbelow 50,000Relative contraindication; evidence is thin — Hibbert et al (Chest 2013) found hemorrhagic complications infrequent even with abnormal coagulation under ultrasound
INRgreater than 2x normalRelative contraindication per WikEM (McVay 1991)
Ultrasound guidanceStrongly recommendedReduces pneumothorax risk

Maximum Safe Removal

  • Traditional limit: ~1.5 L in 24 hr to prevent re-expansion pulmonary edema (RPE)
  • Evidence note: Feller-Kopman (2007) found weak correlation between volume removed and RPE; experienced operators can drain more in monitored patients
  • Stop if: Chest pain, dyspnea, hypotension

Complications

ComplicationRateNotes
Pneumothorax4-19%Lower with ultrasound guidance
Cough~9%Usually self-limited
Re-expansion pulmonary edemaRareRisk may not correlate with volume
HemothoraxRareConsider if chest tube needed
Splenic / liver punctureRareUse ultrasound to mark site

WikEM Thoracentesis | Merck Manual

Paracentesis

Pre-Procedure Labs

  • No pre-procedure labs routinely needed. Bleeding risk below 0.2% even in liver failure with elevated INR
  • Contraindicated only in: Active bleeding or DIC

Maximum Safe Removal

  • Therapeutic: 5-6 L well tolerated; up to 8 L in some patients
  • Stop if: Hypotension, abdominal pain, vasovagal symptoms

Albumin Replacement

Volume RemovedAlbumin DoseRationale
Less than 5 LNone neededLow risk of post-paracentesis circulatory dysfunction
5 L or more6-8 g per liter removed, or 50 g totalPrevents post-paracentesis circulatory dysfunction
SBP or renal insufficiency1.5 g/kgReduces hepatorenal syndrome risk (Kwok 2013 meta-analysis)

SBP Diagnostic Criteria

TestSBP ThresholdNotes
PMN countat least 250 cells/mcLDiagnostic of SBP
CulturePositiveMay be negative if prior antibiotics
SAAGgreater than 1.1 g/dLConfirms portal hypertension as cause of ascites

Complications

ComplicationRateMitigation
Hemorrhage0-0.93%Ultrasound guidance; avoid epigastric vessels
Ascitic leak~5%Z-track technique; pressure dressing
Bowel perforation~0.6%Use blunt-tip needle; avoid midline scars
Infection~0.6%Sterile technique

WikEM Paracentesis | Merck Manual

Arterial Line

Setup

  • 500 mL NS in pressure bag at 300 mm Hg
  • Transducer at phlebostatic axis (4th intercostal space, mid-axillary line)
  • Connect to monitor, open transducer to air, zero, then close
  • Flush and check for air bubbles before use

Zeroing

  • Transducer must be at level of the heart
  • Every 5 cm below the heart = ~3.5 mm Hg over-read
  • Every 5 cm above the heart = ~3.5 mm Hg under-read
  • Re-zero after any position change

Waveform Interpretation

WaveformCharacteristicsCausesAction
NormalSharp upstroke, dicrotic notch, gradual diastolic decline
DampedBlunted upstroke, loss of dicrotic notch, narrowed pulse pressureAir bubbles, clot, kinked catheter, vasospasmFlush and aspirate; check for kinks
OverdampedSlow rise, no dicrotic notch, falsely low systolicAir in line, loose connections, catheter against vessel wallFlush system; tighten connections; reposition catheter
UnderdampedOvershoot, exaggerated dicrotic notch, “ringing” after waveformLong tubing, resonance artifact; overestimates SBP, underestimates DBPUse shorter tubing; add damping device

Dicrotic notch position: Low notch = low SVR; high notch = high SVR

Pearls

  • Preferred site: Radial (check Allen test for collateral flow)
  • Ultrasound guidance increases first-pass success (Shiver 2006)
  • Contraindications: No Doppler or palpable pulse, ipsilateral dialysis fistula, inadequate ulnar collaterals, burns or infection over site
  • Coagulopathy: Radial preferred over femoral; prolonged pressure (10 min) may be needed after removal
  • Hand ischemia: Rare — collateral flow usually protects; thrombosis typically recanalizes after catheter removal

WikEM Arterial line | Merck Manual