Bedside procedure references for central line, lumbar puncture, thoracentesis, paracentesis, and arterial line.
Quick-reference cards for common bedside procedures. See Resources by Technique for NEJM Videos and other multimedia guides.
Central Line (CVC)
Site Selection
| Site | Depth | Key Advantages | Key Risks |
|---|
| Right IJ | ~13 cm (or height / 10) | Best for ultrasound, compressible, lowest pneumothorax | Higher infection than subclavian per 3SITES |
| Left IJ | ~15 cm | Same advantages as right IJ | Pleural dome higher on left |
| Subclavian | ~15 cm right, ~17 cm left | Lowest infection rate (3SITES trial) | Highest pneumothorax risk; contraindicated with ipsilateral clavicle fracture |
| Femoral | ~20-24 cm | Compressible, preferred in coagulopathy | Higher infection historically (3SITES showed similar to IJ); avoid if groin infection |
Catheter Sizes
| Catheter | French Size | Lumens | Typical Flow | Notes |
|---|
| Triple-lumen | 7 Fr | 3 (16 ga, 18 ga, 18 ga) | Standard | Most common CVC |
| Sheath introducer (Cordis) | 8.5 Fr | 1 (plus sideport) | ~7.6 L/hr (20 L/hr with pressure bag) | Fastest non-HD option; for rapid transfusion or PA catheter |
| Dialysis catheter | 11.5-12 Fr | 2 | High-flow | For CRRT or HD |
Sterile Bundle Checklist
Contraindications
- Absolute: Infection over site, anatomic obstruction (thrombosis)
- Relative: Coagulopathy — use compressible site (femoral greater than IJ greater than subclavian). No evidence for prophylactic FFP unless hemophilia or frank arterial puncture
Complications
| Complication | Highest Risk Site | Mitigation |
|---|
| Pneumothorax | Subclavian | Ultrasound guidance; use IJ in ventilated patients |
| Arterial puncture | Femoral | Ultrasound guidance; confirm with manometry |
| Catheter-related bloodstream infection | Femoral (historical) | Maximal sterile barrier; remove when no longer needed |
| Air embolism | Any | Trendelenburg position during insertion; occlude catheter hub |
| Arrhythmia | Any (guidewire) | Advance wire no more than needed; monitor ECG |
| DVT | Femoral | Minimize dwell time |
WikEM CVC | Merck Manual
Lumbar Puncture
Opening Pressure
- Normal: 10-20 cm H2O
- Measure with: Patient in lateral decubitus, legs extended
- Bacterial meningitis: Often greater than 25 cm H2O
CT Before LP Criteria
Safe to proceed without CT if all of the following are met (NEJM 2001 criteria):
- Age below 60
- Not immunocompromised
- No known CNS disease
- No seizure within 1 week
- Alert and following commands
- Normal neurologic exam
CT findings that prohibit LP: Midline shift, obstructive hydrocephalus, compressed basilar cisterns, posterior fossa mass
Platelet and INR Thresholds
| Parameter | Threshold | Action |
|---|
| Platelets | below 25,000 | Transfuse before LP |
| INR | greater than 1.5 | Correct before LP |
| Hemophilia | Any | Replace factor pre-procedure |
Tube Order
| Tube | Study | Notes |
|---|
| Tube 1 | Cell count and differential | Most likely to have traumatic blood |
| Tube 2 | Gram stain, culture (bacterial + viral) | Sterile tube for microbiology |
| Tube 3 | Glucose, protein | Least affected by traumatic tap |
| Tube 4 | Second cell count or hold | For special tests: crypto Ag, AFB, VDRL, PCR |
Bloody tap correction: Subtract 1 WBC per 750 RBC; subtract 1 mg/dL protein per 1000 RBC
CSF Interpretation
| Pattern | WBC | Differential | Glucose | Protein |
|---|
| Bacterial | greater than 100 | PMN 80-90% | Low (below 40) | High (greater than 100) |
| Viral | 5-500 | Lymphocytes | Normal | Normal to mildly elevated |
| Fungal / TB | 10-500 | Lymphocytes | Low | High |
| Subarachnoid hemorrhage | RBCs present | PMN early | Normal | Elevated |
Pearls
- Atraumatic 22-ga needle reduces post-LP headache (2018 Lancet meta-analysis). Needle larger than 20 ga doubles headache risk
- CSF cultures may be negative 2 hr after parenteral antibiotics (meningococcal) or 6 hr (pneumococcal)
- Needle gauge: use 22 ga atraumatic when available; reserve 20 ga for obese patients or when opening pressure is critical
WikEM LP | Merck Manual
Thoracentesis
Pre-Procedure Labs
| Parameter | Threshold | Notes |
|---|
| Platelets | below 50,000 | Relative contraindication; evidence is thin — Hibbert et al (Chest 2013) found hemorrhagic complications infrequent even with abnormal coagulation under ultrasound |
| INR | greater than 2x normal | Relative contraindication per WikEM (McVay 1991) |
| Ultrasound guidance | Strongly recommended | Reduces pneumothorax risk |
Maximum Safe Removal
- Traditional limit: ~1.5 L in 24 hr to prevent re-expansion pulmonary edema (RPE)
- Evidence note: Feller-Kopman (2007) found weak correlation between volume removed and RPE; experienced operators can drain more in monitored patients
- Stop if: Chest pain, dyspnea, hypotension
Complications
| Complication | Rate | Notes |
|---|
| Pneumothorax | 4-19% | Lower with ultrasound guidance |
| Cough | ~9% | Usually self-limited |
| Re-expansion pulmonary edema | Rare | Risk may not correlate with volume |
| Hemothorax | Rare | Consider if chest tube needed |
| Splenic / liver puncture | Rare | Use ultrasound to mark site |
WikEM Thoracentesis | Merck Manual
Paracentesis
Pre-Procedure Labs
- No pre-procedure labs routinely needed. Bleeding risk below 0.2% even in liver failure with elevated INR
- Contraindicated only in: Active bleeding or DIC
Maximum Safe Removal
- Therapeutic: 5-6 L well tolerated; up to 8 L in some patients
- Stop if: Hypotension, abdominal pain, vasovagal symptoms
Albumin Replacement
| Volume Removed | Albumin Dose | Rationale |
|---|
| Less than 5 L | None needed | Low risk of post-paracentesis circulatory dysfunction |
| 5 L or more | 6-8 g per liter removed, or 50 g total | Prevents post-paracentesis circulatory dysfunction |
| SBP or renal insufficiency | 1.5 g/kg | Reduces hepatorenal syndrome risk (Kwok 2013 meta-analysis) |
SBP Diagnostic Criteria
| Test | SBP Threshold | Notes |
|---|
| PMN count | at least 250 cells/mcL | Diagnostic of SBP |
| Culture | Positive | May be negative if prior antibiotics |
| SAAG | greater than 1.1 g/dL | Confirms portal hypertension as cause of ascites |
Complications
| Complication | Rate | Mitigation |
|---|
| Hemorrhage | 0-0.93% | Ultrasound guidance; avoid epigastric vessels |
| Ascitic leak | ~5% | Z-track technique; pressure dressing |
| Bowel perforation | ~0.6% | Use blunt-tip needle; avoid midline scars |
| Infection | ~0.6% | Sterile technique |
WikEM Paracentesis | Merck Manual
Arterial Line
Setup
- 500 mL NS in pressure bag at 300 mm Hg
- Transducer at phlebostatic axis (4th intercostal space, mid-axillary line)
- Connect to monitor, open transducer to air, zero, then close
- Flush and check for air bubbles before use
Zeroing
- Transducer must be at level of the heart
- Every 5 cm below the heart = ~3.5 mm Hg over-read
- Every 5 cm above the heart = ~3.5 mm Hg under-read
- Re-zero after any position change
| Waveform | Characteristics | Causes | Action |
|---|
| Normal | Sharp upstroke, dicrotic notch, gradual diastolic decline | — | — |
| Damped | Blunted upstroke, loss of dicrotic notch, narrowed pulse pressure | Air bubbles, clot, kinked catheter, vasospasm | Flush and aspirate; check for kinks |
| Overdamped | Slow rise, no dicrotic notch, falsely low systolic | Air in line, loose connections, catheter against vessel wall | Flush system; tighten connections; reposition catheter |
| Underdamped | Overshoot, exaggerated dicrotic notch, “ringing” after waveform | Long tubing, resonance artifact; overestimates SBP, underestimates DBP | Use shorter tubing; add damping device |
Dicrotic notch position: Low notch = low SVR; high notch = high SVR
Pearls
- Preferred site: Radial (check Allen test for collateral flow)
- Ultrasound guidance increases first-pass success (Shiver 2006)
- Contraindications: No Doppler or palpable pulse, ipsilateral dialysis fistula, inadequate ulnar collaterals, burns or infection over site
- Coagulopathy: Radial preferred over femoral; prolonged pressure (10 min) may be needed after removal
- Hand ischemia: Rare — collateral flow usually protects; thrombosis typically recanalizes after catheter removal
WikEM Arterial line | Merck Manual